The Sanctuary of Santa Maria in Basilico dates back to the eiegth century A.D., when it belonged to the Benedictine Abbey of San Vincenzo al Volturno. At a later date The Order of San Benedetto abandoned this settlement and in the patronage of the Church succeeded the Caracciolo family, which arranged to renovations and extensions until the nineteenth century. The Sanctuary rises isolated in the countryside, near the shore of the Sangro river. It has a complex structure, consisting of five different volumes for height and projecting to varying degrees, according to the three inner aisles and the side chapels.  The single gateway is made of red bricks, supported by two rectangular pillars and closed above by a segmental arch. A composite frame, also of brick, completely surrounds it. In the inside, a series of pillars with arches divides the interior into three aisles. All around runs an entablature supported by gilded capitals. The center aisle, the transect and the apse have a barrel vault with transverse arches and lunettes. The ceiling is decorated with paintings framed in stucco. On the main aisle rises a hemispherical dome on four plumes, but without lantern; it is decorated with degrading chests of drawers towards the center. The side aisles have vaults set on arches. In the chapels you can notice covered vaults and decorations in stucco.
The superior altar is structured with two columns each side supporting a horizontal entablature; above, a circular oculus classified by scrolls, frames, cupids and garlands. At the center, in a niche, stands the ancient statue of the Madonna and Child.
The Sanctuary also preserves nineteenth century paintings of painters Francesco Maria De Benedictis and Ferdinando Palmerio of Guardiagrele.